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In general, mature T cells exiting the thymusand present in the circulation and secondary lymphoid tissue(lymph nodes and spleen) are characterized by the presenceof CD3+ and either CD4+ or CD8+ surface markers and aredevoid of surface or cytoplasmic Ig. The RCT remainsthe ‘gold standard’ of EBP, while evidence-based or lay knowledge and qualitative methods areafforded a lesser place The RCT remainsthe ‘gold standard’ of EBP, while evidence-based or lay knowledge and qualitative methods areafforded a lesser place. The design variables involved in creating an animal model for bone and jointinfection are multiple and inevitably require some compromise. (2005).The global burden of oral diseases and risk to oral health.
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